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Since isolated primary human islets cannot be cultured for extensive periods of time and exhibit donor-to-donor variability, most groups have historically relied on rodent models and cell lines to robustly understand the genetic and mechanistic components involved in the initiation and progression of T1D
doi: 10.1039/C2FO30139C 38 BansalPPaulPMudgalJG
the Regulatory Flexibility Act (RFA) (Pub
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