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Less commonly, angular cheilitis is associated with primary hypervitaminosis A, [20] which can occur when large amounts of liver (including cod liver oil and other fish oils) are regularly consumed or as a result from an excess intake of vitamin A in the form of vitamin supplements

Finally, we evaluated only the EZH2 and H3K27me3 proteins and not EZH2 and H3K27me3 mRNAs in cells exposed to cigarette smoke, since as previously showed 17 , this methodological approach seems to be adequate to define the epigenetic modifications of DAB2IP gene, by the action of methyl transferase EZH2 on H3K27 trimethylation in lysine 27

A cigarette break