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While such studies have provided valuable insights into the potential positive public health impact of smoke-free products, the use of diverse datasets for transition modeling has resulted in inconsistent definitions of product use scenarios

In line with the increased nicotine concentration in the e-liquids, increasing and high cotinine levels in saliva were observed [17], and high cotinine levels in saliva indicate a potentially high cotinine content in e-liquids sold on the local market

Quitting a substance cold turkey may seem like the quickest path to recovery, but for many, it can also be the most dangerous

Multivariate restricted cubic spline analyses suggested a J-shape association between the average daily consumption of machine-rolled cigarettes and the risk of hypertension (Figure 1A)