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A fourth character provides greater specificity to this code: J44 Other chronic obstructive pulmonary disease includes asthma with COPD, chronic asthmatic bronchitis, and chronic obstructive asthma, among other diagnoses J44.0 COPD with (acute) lower respiratory infection used to report cases where a patient with COPD develops an acute infection in the lower respiratory tract, such as bronchitis or pneumonia J44.1 COPD with (acute) exacerbation used when the patient experiences worsening COPD symptoms (e.g., increased dyspnea, wheezing) without an infection J44.0 and J44.1 are assigned together when documentation shows a patient with an acute lower respiratory infection as well as an acute exacerbation

Several have been identified are carcinogenic, mutagenic, or teratogenic

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When these Fagerstrm test scores are classified according to 5 cutoff points, we see that "very low dependence" ( n = 75, 46.3%) is the highest (Fig