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Temple was already an established star, while Judy Garland, who eventually got the role, had only just started at MGM a couple of years earlier

PMI has carefully overhauled its image with a new mission: "designing a smoke-free future." Since 2008, PMI has invested more than $6 billion on iQOS, its heated tobacco device and other next-generation products

It should be noted that our study did not find clear dose-response associations between maternal smoking before or during the pregnancy and birth congenital anomalies, similar to a previous study on maternal smoking and congenital heart defects by Alverson et al

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