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Advances of EVs as biological biomarkers Although the traditional tissue biopsies remains the gold standard for disease diagnosis, the procedure is invasive and commonly constrained by its repeatability and brings economic and mental burden to patients [37, 38]

MCDPH uses the International Classification of Diseases, 10th revision (ICD-10) code listed as the underlying cause of death on county resident death certificates to identify fully alcohol-attributable deaths

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