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Supplementation of CR lo and CR hi cell lines with CR itself did not alter their proliferation rate (Supplemental Figure 2, AD), despite the detection of extracellularly supplied CR within the intracellular metabolite pool (Supplemental Figure 2E), indicating that CR is a cancer cellderived biomarker that accumulates with cell proliferation but does not itself induce functional effects

The shift to 25 g packs for some varieties has added even more diversity, while the well-loved 200 g tins remain available

Exposure to the hidden toxins in thirdhand smoke leaves people at risk, even if they dont smoke

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