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Withdrawal of semaglutide led to weight regain, highlighting the chronic nature of obesity and the need for long-term treatment strategies (Rubino, Diabetes, Obesity and Metabolism )

Many I spoke to hadn't told even their partners, family or close friends they were taking the medications, let alone complained of the side effects

Clinical evidence demonstrating superior HbA1c reduction efficacy, weight loss benefits, and cardiovascular event reduction has elevated Semaglutide's status among primary care prescribers, endocrinologists, and insurance formulary committees

Additionally, symptoms such as unexplained weight loss, rectal bleeding, or a significant change in bowel habit (especially in those over 50) may warrant investigation for more serious conditions in line with NICE guidance on suspected cancer recognition and referral