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Moreover, DCP is used as a tumor screening and diagnostic biomarker owing to its sensitivity and specificity

We reasoned that the exercise-induced damage and infiltration of immune cells might be due to mitochondrial DNA (mtDNA) fragments circulating in the systemic circulation, that act as a damage-associated molecular pattern triggering a systemic inflammatory response 33,34,35,36

Both MASH and liver fibrosis are significant risk factors for the onset of cirrhosis and hepatocellular carcinoma, leading causes of liver transplantation [4, 5] and responsible for over 800,000 deaths worldwide [6]

Timing and sequencing of peptide interventions are crucial for optimal results