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Researchers found that, among smokers ages 12 to 17, the percentage who had depression increased from 16.0 percent in 2005 to 22.4 percent in 2013

More recent work supports this hypothesis, with Shah [69] demonstrating albuminuria and abnormal renal function in tobacco chewers and Gupta et al.[70] indicating that chewers had systolic and diastolic blood pressures, resting heart rates, total cholesterol, LDL cholesterol and triglycerides comparable to smokers

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