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Regarding dosage strength , while higher maintenance doses (10 mg or 15 mg weekly) result in higher initial concentrations in the bloodstream, the half-life and elimination rate remain consistent across doses

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Therefore, we investigated the role of B12 deficiency on lipid metabolism and inflammatory mediators in both in vitro and ex vivo models including human pre-adipocytes, primary adipocytes, mature human white AT (WAT), and its association with metabolic risk

Trial products were manufactured and supplied by Novo Nordisk A/S (Bagsvaerd, Denmark)