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Nanobiotechnology 19, 205

In contrast, Zepbound (tirzepatide) is emerging as the fastest-growing product

PI3K/Akt/mTOR Signaling The two primary signaling pathways activated by IGF-1 DES through IGF1R are the PI3K/Akt/mTOR axis and the Ras/Raf/MEK/ERK MAPK cascade, both of which drive anabolic processes, cell survival, proliferation, and metabolic reprogramming