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doi:10.1016/j.cvsm.2008.04.012

When exposed to chronic alcohol-induced inflammation, HSCs become activated, transdifferentiating into myofibroblasts.10 These myofibroblasts are responsible for the excessive production of extracellular matrix (ECM) components, which leads to liver fibrosis, a key feature in the transition from early stage ALD to cirrhosis.10 The intricate and multifaceted pathogenesis of ALD also involves various other mediators that contribute to inflammation and fibrosis

Pharmacogenetics 2004;14:539-47

Timing your injection to avoid peak hunger periods or when you have nutritious food readily available can reduce discomfort