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This can cause bile to sit longer in the gallbladder, becoming more concentrated

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If you already understand what compound tirzepatide is and want to know about safety concerns, skip to "Compounded tirzepatide safety risks you should know." Tirzepatide works as a dual agonist, meaning it targets two hormone receptors: Dual agonist mechanism: Tirzepatide activates both glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP) receptors to reduce appetite and slow digestion Compounding process: Pharmacies mix tirzepatide powder for compounding into injectable or sometimes oral formulations Key distinction: Compounded versions are not the same as FDA-approved Mounjaro or Zepbound The dual mechanism is what sets tirzepatide apart from single-agonist medications like semaglutide

Another reported effect has been growth of lymphoid tissue (specially acromegaly and tonsillar hypertrophy), renal enlargement (with normal kidney function) and in rare cases facial coarsening of features and incremented hair growth [264]