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Nicotine Withdrawal Psychological Symptoms: Sleep disturbances (dyssomnias, mainly insomnia) and fatigue Restlessness Concentration problems Nervousness and irritability Anxiety or concern Dysphoric mood (anxious, depressed, or irritable) Depression Nicotine Withdrawal Physical Symptoms: Rapid heartbeat (tachycardia) and palpitations Dizziness and nausea Headache Diarrhea Psychomotor agitation Tremor Shortness of breath (dyspnea) Excessive sweating (hyperhidrosis) Intense hunger (hyperphagia) Nicotine Withdrawal Sleep Disturbances Sleep disturbances during nicotine withdrawal are particularly common, potentially worsening daytime fatigue and dysphoria, making relapse more likely

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The pooled data of all five studies showed an association that was not statistically significant (odds ratio, 1.69