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The FTO gene variant rs9939609, for example, affects metabolic rate and heat production independent of weight, which means some patients may feel colder than others at the same dose and weight loss stage

Very common side effects include [4, 5]: Liraglutide: Nausea Diarrhoea Constipation Headache Fatigue Semaglutide: Nausea Vomiting Constipation Abdominal pain Headache Fatigue Serious side effects of both medications may include severe abdominal pain which could be a sign of pancreatitis, gallbladder problems, or very low blood sugar (especially in people also taking diabetes medications)

In addition, they can also provide some level of protection against other environmental factors such as wind and cold

Multicopy integration of heterologous genes, using the lactococcal group II intron targeted to bacterial insertion sequences