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Treatment of patients with type 2 diabetes and non-alcoholic fatty liver disease: current approaches and future directions

Tumori 2005

472,473 To overcome the heterogeneity and adaptability of tumor metabolism, enhance the specificity of targeted drugs, minimize adverse effects, and hinder the occrurence of treatment resistance, novel investigations in targeted therapy focus on devising novel small-molecule inhibitors, developing robust delivery systems that adhere to the 3 R delivery principle (right site, right timing and right dose) and exploring rational and effective drug combination strategies

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