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Consideration should be given to changing the therapeutic regimen, including possibly discontinuing the medication, in patients whose depression is persistently worse, or who are experiencing emergent suicidality or symptoms that might be precursors to worsening depression or suicidality, especially if these symptoms are severe, abrupt in onset, or were not part of the patients presenting symptoms

(Berl.) 206 , 303312 (2009)

Zhao H, Larson C, Schepergerdes BJ, Diefendorf CM, Ortega-Loayza AG, Mostaghimi A

If each crave is less than 3 minutes and the average quitter experiences a maximum of 6 on their most challenging day, can you handle 18 minutes of challenge