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The missense variants p.Thr165Ala in MTARC1 and p.Ile43Val in GPAM had the greatest similarity in their associations with the tested traits (Figs

fumigatus to maintain fitness and homeostasis

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Besides the already discussed actions of IGF-1 on glucose, it also has an indirect glucose-lowering effect secondary to its ability in increasing FA oxidation in muscle (will be further discussed in detail within the IGF - 1 and lipid metabolism section)