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Support ellagic acid therapy in patients with hormone refractory prostate cancer (HRPC) on standard chemotherapy using vinorelbine and estramustine phosphate

In addition, when mitochondrial dysfunction occurs, the intrinsic apoptotic pathway mediated by mitochondrial signaling is difficult to carry out and therefore fails to regulate apoptosis of primordial germ cells (PGC), which may lead to abnormal migration of PGC into the gonads, adversely affecting the male reproductive system (Bejarano et al

PMID: 36917520

He says that when patients BACs are at these extreme highs, thats when they develop intoxicated delirium theyre so intoxicated that they can develop brain dysfunction, are in a stupor to the point they need intubation, or are in agitated deliriummeaning so incredibly violent that they need to be put in restraints and medicated with Haldol, because theyre attacking staff or patients. (Haldol is an antipsychotic medication.) In one instance, Dr