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For Stage 3 and 4 Candida overgrowth, biofilm-disrupting enzymes are administered before antifungal agents to dismantle the polysaccharide matrix protecting established Candida colonies

Gene-Associated Pathways were identified using the Enrichment_rank of the pathways based on their statistical significance ( P values) of KEGG pathway enrichment analyses for AD-associated genes from different sources: Enrichment_rank_1 used AD-associated genes from Open Targets, and Enrichment_rank_2 used genetically associated AD genes identified in genome-wide association and familial studies

Clinical Trial Registration Dates include (DD/MM/YYYY): First Submitted, 17/06/2021