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The permeability of the small hydrophilic marker dye fluorescein was at the level of non-treated control (4.75 10 6 cm/s) in all groups at basal conditions which was significantly increased by 40% after cytokine treatment (Fig

Low levels of GSH also correlate with a compromised immune response by altering cytokine production, where decreased GSH is associated with reduced levels of IL-12, IL-2, and IFN-, which play pivotal roles in immune regulation

Collectively, we report a scalable, generalizable platform for dissecting peptide-specific KIR recognition across HLA-I allotypes, with clear utility for mechanistic studies and translational applications

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