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Cellular signaling studies, tissue biology research, and gastrointestinal biology investigations are some of the areas that researchers are investigating regarding this peptide

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Research has indicated that compounds targeting TRP channels, such as vanillin, capsaicin and capsazepine, can reduce reactive astrocyte activity, which in turn can mitigate A toxicity in the early stages of AD 154

In these contexts, it was proposed that NCC may act as a receptor for interleukin 18 (IL-18), potentially collaborating with receptors for the incretin glucagon-like peptide 1 (GLP-1) to enhance -cell mass and help maintain glucose homeostasis (Zhang et al., 2022b)