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A 2024 narrative review highlighted what the authors called a growing problem of off-label drug use among athletes, who often feel pressured to experiment with anything that may confer an advantage

It is crucial to follow the prescribed dosage and administration instructions strictly and seek medical advice if any concerns or questions arise during the course of treatment

It is also more light-sensitive than cyanocobalamin, which means formulations containing methylcobalamin may have additional light protection requirements and potentially shorter shelf lives if not stored properly in opaque containers

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