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Within each active month, the 5-days-on, 2-days-off schedule follows the same logic at the weekly level: it prevents tachyphylaxis (diminished response from constant exposure) while maintaining enough stimulus frequency to produce measurable visceral fat reduction

Cohort 1 participants received a SARS-CoV-2 negative result on screening immediately after contact with the infected cohabitant and had a negative RT-PCR and serological result prior to study initiation

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