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Its presence in bile was further validated by reanalysis of bile 16S rRNA datasets (Supplementary Tables S2, S3)

The Fc domain not only provides steric protection against proteolytic enzymes but may also reduce immunogenicity by minimizing the generation of anti-drug antibodies

Zhang Y, Gao J, Chung KK, Huang H, Dawson VL, Dawson TM (2000) Parkin functions as an E2-dependent ubiquitin- protein ligase and promotes the degradation of the synaptic vesicle-associated protein, CDCrel-1