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The oxidative stress is the result of the imbalance of the antioxidant system in favor of prooxidants, which interferes with the GSH/GSSG system in the antioxidant defense and the regulation of gene expression, the synthesis of DNA and proteins, cell proliferation and apoptosis, and cytokine production and protein glutathionylation, due to alteration of certain cellular functions

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Gastrointestinal side effects are the most common adverse reactions to Saxenda, affecting a significant proportion of patients, particularly during the initial titration phase

The inhibition of xanthine oxidase blocks the conversion of MP into thiouric acid[5658]