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CBD2 receptors are located in the immune system and are involved in the regulation of inflammation and pain

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(On Trial) | Denmark Clutch Clutch (East West) | USA Acrimony The Acid Elephant EP (Godhead) | UK | Bandcamp Red Giant Psychoblaster and the Misuse of Power (Red Giant) | USA Tumbleweed Galactaphonic (Polydor) | Australia Heavy Metal Doom metal pioneers Trouble took their shot at crossing over to a larger audience with the help of Rick Rubin on their fourth and fifth albums Trouble (1990) and Manic Frustration (1992)