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Caffeine "Heart palpitations are a potential concern with supplements containing green tea, guarana, yerba mate, or kola nut all ingredients that naturally contain caffeine," says Tod Cooperman, MD, the president of ConsumerLab, an independent testing company in White Plains, New York, focused on health and nutrition products

Pineal Gland Signaling and Melatonin Rhythm Modulation The AEDG sequence was originally derived from epithalamin, a polypeptide extract of the bovine pineal gland, and a significant body of research has investigated its interactions with pineal function specifically melatonin synthesis and circadian rhythm regulation