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Its activity has been associated with reduced permeability disturbances and improved resistance to mucosal injury, particularly in models involving non-steroidal anti-inflammatory drug exposure (10)

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Results : Glutathione, catalase and total protein levels in Amethopterin and self-treated groups showed a significant decrease when compared with control group, while MDA levels in Amethopterin and self-treated groups showed a significant increase when compared with control group