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"It's never too late to make a positive change for your health and there are a range of effective products and treatments that can help smokers quit for good." Health officials have said that smokers can find advice, support and resources with the NHS Quit Smoking app, as well as the online Personal Quit Plan

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As sensation seeking has long been implicated in the reinforcing effects of psychostimulants 52 , we thus proposed a reinforcement loop underlying the maintenance of smoking, where smoking behaviour could reduce GMV in the right vmPFC, leading to disinhibited reward-seeking behaviour (i.e., higher sensation seeking), and hence, in turn, promote future smoking behaviour