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PMID: 28813125 Vreman RA, Goodell AJ, Rodriguez LA, Porco TC, Lustig RH, Kahn JG
Co-CEO and co-founder Justin Klee said the deal came after Amylyx checked out hundreds of assets over the last few years, and its closing brought added attention to phase III-ready, first-in-class avexitide
Engagement of this receptor primarily initiates phospholipase C dependent signaling and intracellular calcium mobilization within somatotroph cells, supporting its utility in mechanistic investigations of growth hormone release dynamics (7,13)