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A novel mouse model was generated to explore whether maintaining intact BSCL2 expression in the liver prevents the onset of metabolic disorders in mice with specific BSCL2 deficiency in adipose tissue

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Inhibition of endoplasmic reticulum (ER) stress can stop pancreatic tissue damage.[ref] Other researchers point to alterations in autophagy in addition to inflammation as a cause of pancreatitis.[ref] Lets dig deeper into the research on inflammation and then take look at autophagy and the gut microbiome: Inflammation in Pancreatitis: In the inflammatory cascade that occurs with pancreatitis, damaged cells activate pathways that increase inflammation, including HMGB1, TLR4 (toll-like receptor 4), TLR9, and heat shock protein 70

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