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The graveyard of neuroprotection and neurorestoration is full of compounds that improved rat stroke scores and then failed in humans

Although there have been no specific trials to show cardiorenal benefit for GLP-1RA or SGLT2i when used as first-line therapy or as monotherapy or in newly diagnosed T2D, the benefit seen in the CV outcome trials has not been found to vary with the duration of diabetes, suggesting that similar benefits might be seen early in the course of disease.4 The benefits are also not dependent on the presence of metformin

Vitamin C (Ascorbic Acid) A water-soluble antioxidant involved in collagen synthesis, which is relevant to connective tissue repair following eccentric loading and tissue micro-trauma

Elevated periostin in serum and peritoneal washing fluids as potential biomarkers for endometriosis