A hydrogen bonding reinforced factor, imidazolidinyl urea (IU), was introduced into polyurethane to produce multiple hydrogen-bond mediated hydrogel (PMI) by polyaddition with poly (ethylene glycol) (PEG) and methylene diphenyl 4,4-diisocyanate (MDI) (Supplementary Fig
[DOI] [PMC free article] [PubMed] [Google Scholar] 3.Iqbal J., Huang G.D., Xue Y.X., Yang M., Jia X.J
Microbial Dysbiosis Modulates Protein Clearance Mechanisms, Autoimmune Functions, and Central Nervous System Immune Recruitment Aggregated misfolded protein and autophagolysosomal-proteasomal pathways participate in a vicious cycle that causes cytotoxicity and exacerbates hallmark pathologies of neurodegenerative disorders (Monaco and Fraldi, 2020)
Khoruts A, Staley C, Sadowsky MJ