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Produced by adipose tissue, endothelial cells, and immune cells in response to hyperglycemia, IL-6 levels are elevated in diabetic patients, where they play a role in insulin resistance and chronic inflammation (1)
In cultured astrocytes, the truncated isoform of the TrkB receptor (TrkB-T1, also known as TrkB-Tc) mediates rapid intracellular Ca 2+ transients in response to brief BDNF exposure
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