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Anecdotally, it is used for targeted abdominal fat loss, but the results are inconsistent and highly dependent on diet and exercise

The percentage of patients who responded to treatment increased from 34% to nearly 39% after one year (Rotaru et al., 2020)

Typically, CAFs overexpress alpha-smooth muscle actin (-SMA), Vimentin, platelet-derived growth factor receptor (PDGFR), PDGFR, Tenascin-C, Caveolin 1, fibroblast activation protein (FAP), and ferroptosis suppressor protein 1 (FSP1) [66]