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Naltrexone-bupropion (Contrave) combines an opioid blocker with an antidepressant to help control appetite and may work better for emotional or reward-based eating, says Rao

Over a period of time, KD has been evaluated in 2 uncontrolled and 1 placebo-controlled clinical trial, while AMD has been evaluated in 1 clinically controlled open-labeled clinical trial for its efficacy against ASD [165]

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The peptide chelates free copper ions that could otherwise participate in pro-oxidant Fenton reactions, while simultaneously stimulating the expression of endogenous antioxidant enzymes such as superoxide dismutase, catalase, and glutathione peroxidase