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13,14 Owen and colleagues conducted a retrospective study of 91 patients with nonsmall-cell lung cancer who received a PD-1/PD-L1 inhibitor, 13 and Eun and colleagues conducted a retrospective study of 391 patients who received the PD-1 inhibitor pembrolizumab

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Very high doses of B12 taken orally may occasionally cause mild gastrointestinal disturbance in some individuals, though this is uncommon

Researchers at the University of British Columbia said the conditions in the study include one disorder not named in the warning labels for those drugs: stomach paralysis, which slows or completely stops the movement of food from the stomach to the intestine and can cause symptoms like persistent vomiting