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Those with a history of kidney disease, autoimmune conditions, or severe malnutrition may have altered glutathione metabolism and require careful assessment
It is especially important for liver function
Note: No significant changes in bone turnover markers (osteocalcin and bone-specific alkaline phosphatase) were observed in studies (PMID: 10373343, PMID: 10828840)
Patients should seek urgent medical attention if they experience severe persistent abdominal pain (which may indicate pancreatitis), persistent vomiting/dehydration, jaundice, acute visual changes, or hypoglycaemia if on insulin or sulfonylureas
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