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In fact, polylysine at alkaline pH and polyglutamic acid at acid pH form -helical conformations, since under these conditions they have neutral side chains, whereas at high pH and high temperature, polylysine adopts an extended, flat, multistranded -sheet conformation, and polyglutamic acid forms -sheet structure at low pH
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33 The discogenic pain signal passes through the IVD and adjacent structures and is transmitted through peripheral afferent nerve fibers
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