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However, due to the much more efficient oxidation of formic acid in non-primates, due to the high activity of 10-CHO-THF, which in humans only reaches 26% of that observed in rodents, models using non-primates did not fully allow simulate the human conditions (Chen et al

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Lpez-Velzquez JA, Silva-Vidal KV, Ponciano-Rodrguez G, Chvez-Tapia NC, Arrese M, Uribe M, et al

Advancement of scaffold-based 3D cellular models in cancer tissue engineering: an update