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In the present study, TPH1 null mice were more susceptible than controls to acetaminophen-and NAPQI-induced lipid peroxidation, as evidenced by increased MDA and MPO levels and reduced GSH and GSH-px in the liver tissues which were also important antioxidant enzymes
Certain groups of researchers have also demonstrated the protective mechanism of Vitamin E against oxidative stress-mediated lead toxicity
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