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Strumila R, Nobile B, Korsakova L, Lengvenyte A, Olie E, Lopez-Castroman J, et al
Further studies should explore the regulatory molecular mechanisms in order to update GLS1 inhibitors and develop effective GLS2-activating strategies
As a smaller molecule than GBCAs, water passes the BBB more easily and can detect loss of AQP-4 in preclinical AD (Shao et al., 2019, 2020)
Think of the mental health issues where there's an excess of activity: OCD - excessive, repetitive thoughts ADHD - excessive mental activity Anxiety - hyperactive amygdala (fear and emotional processing center) Bi-polar - manic phase Some of these are expressions of hyperactivation in certain brain areas
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