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In a recent, large clinical trial involving more than 17,000 adults living with overweight or obesity and established heart disease, participants who received a weekly semaglutide injection experienced a 20% reduction in major adverse cardiovascular events (MACE), such as heart attack and stroke, compared to those who didnt take the medication

Without structured resistance training, the 25% lean mass loss fraction may increase further

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Once activated, T lymphocytes secrete pro-inflammatory cytokines such as interferon- (IFN-), interleukin-2 (IL-2), and tumor necrosis factor- (TNF-), which drive tissue damage