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Despite more than 500 published preclinical studies (primarily animal and cell-culture models from Sikiric and colleagues at the University of Zagreb), there have been essentially no registered human clinical trials for BPC-157 in the United States

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Maillot et al [18] observed a higher incidence of AEs in the surgical group, with 3 patients (23.1%) experiencing severe complications (one parietal defect, one abscess requiring a new intervention 2 weeks after surgery and 4 days of hospitalization complicated by severe chronic pelvic pain