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We can't stress this enough: the idea that BPC 157 acts like a topical cream applied from the inside is a simplification that misses the bigger picture of how this peptide actually works

DSIP Administration and Dosage DSIP is typically administered through subcutaneous or intramuscular injections, and because it has a short half-life, it is often used before sleep or during periods of high stress

Curr Psychiatry Rep

They will also set an upper limit on the total weekly dose (for example, some experts recommend not exceeding approximately 300 mg per week in subcutaneous dosing without further evaluation) to minimize any risk of adverse effects