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However, the data presented here clearly demonstrate that in isolated human islets, tirzepatide requires the GIPR to stimulate both insulin and glucagon secretion

10.1103/PhysRevLett.90.228101 47 GuR.-X.BaoukinaS.TielemanD

These effects are particularly evident through decreased malondialdehyde (MDA) levels and increased glutathione (GSH) levels, which help prevent oxidative injury to kidney cells (Akter et al