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The clinical uptake of biomarkers for diagnosing HFpEF has generally been poor, with only cardiac natriuretic peptides (NPs) having emerged as clinically relevant.1 Indeed, current European Society of Cardiology (ESC)/Heart Failure Association guidelines provide a class IB recommendation for NPs for diagnosis of suspected HF and NPs are a major criterion for establishing the diagnosis of HFpEF.1 In this review we discuss identified HFpEF biomarkers derived from different pathological pathways

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2 , S1S5 (2017)