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double-blind, randomized, sham-controlled study) have shown a symptomatic benefit on ataxia scores (SARA and ICARS) and quantified measurements such as the 8-m walking time and performance scores from the nine-hole peg test [215, 216]

These studies often employ daily or twice-daily dosing regimens for periods spanning days to weeks, depending on the condition under investigation, such as tissue repair or gastrointestinal healing